citrus essential oils list

-Terpineol has anticarcinogenic activity [187]. Dosoky N.S., Moriarity D.M., Setzer W.N. Raina A., Bland J., Doolittle M., Lax A., Folkins M., Raina A., Bland J., Doolittle M., Lax A., Boopathy R.A.J., et al. Lemon EO showed cytotoxic effects against human prostate, lung, and breast cancer cells [90]. optimised for 1024 x 768 resolution. The endothelial component is mediated by the nitric oxide to soluble guanylyl cyclase pathway, while the smooth muscle component involves inhibiting extracellular Ca2+ influx and store-operated Ca2+ release mediated by the ryanodine receptor (RyR) signaling pathway [76]. Oils can be extracted by steam distillation or cold expression. The high citral content of lime EO causes potential toxic and myelotoxic effects [110]. Sweet orange, bitter orange, mandarin, and grapefruit EOs are rich in monoterpenes with the major component being d-limonene (65.395.9%) (Table 1) [8]. It has been reported to have anti-spasmodic effect and to enhance sexual desire [59]. It has been used in treating insomnia, epilepsy, and seizures [72]. Saiyudthong S., Marsden C.A. Essential Oil SafetyA Guide for Health Care Professionals. Because of their high economic importance, numerous studies have investigated the chemical composition of the peel, leaf, and flower essential oils of different Citrus species. It showed a 100% singlet oxygen scavenging activity at all concentrations between 0.1 and 2% [20,78]. Due to the presence of limonene, bitter orange EO possesses its gastroprotective and ulcer healing actions through increasing the gastric production of mucus, which is useful as a secondary intervention in the treatment of chronic inflammatory diseases [60]. Interestingly, the essential oil (EO) is the most vital by-product of Citrus processing. table below is a compilation of the most common citrus oils. Determination of bactericidal efficacy of essential oil extracted from orange peel on the food contact surfaces. Akpinar B. Careers. Effects of long-term exposure of lemon essential oil odor on behavioral, hormonal and neuronal parameters in male and female rats. The potent antioxidant effect could be attributed to the high d-limonene content [12,13]. The diluted oil is used to treat pimples and acne [53]. Bitter orange EO showed good radical-scavenging activity [53], largely due to the high d-limonene content [12,13] and its microencapsulated form, which was effective in reducing oxidative stress in acute otitis media rats [61]. Dugo P., Mondello L., Proteggente A.R., Cavazza A., Dugo G. Oxygen heterocyclic compounds of bergamot essential oils. Writing-Original Draft Preparation, N.S.D. Limited data suggests minimal toxicity. Ceccarelli I., Masi F., Fiorenzani P., Aloisi A.M. Yuzu odor promotes mind and body health in Japan [152]. Citrus Smaller resolutions may cause the and transmitted securely. -Pinene was classified as a category B substance in Germany, meaning it is considered moderately allergenic [196]. Essential oil from, Shafreen R.B., Lubinska M., Raska A., Dymerski T., Namienik J., Katrich E., Gorinstein S. Human serum interactions with phenolic and aroma substances of Kaffir (, Spadaro F., Costa R., Circosta C., Occhiuto F. Volatile composition and biological activity of key lime, Tundis R., Loizzo M.R., Bonesi M., Menichini F., Mastellone V., Colica C., Menichini F. Comparative study on the antioxidant capacity and cholinesterase inhibitory activity of, Amorim J.L., Simas D.L.R., Pinheiro M.M.G., Moreno D.S.A., Alviano C.S., Da Silva A.J.R., Fernandes P.D. Furthermore, Citrus EOs are used as natural preservatives due to their broad spectrum of biological activities including antimicrobial and antioxidant effects [9]. It is neither irritating nor sensitizing [167]. It also decreased the overall symptoms of premenstrual syndrome (PMS) in university students. Due to its free radical-scavenging properties, bitter orange extract showed nephroprotective effects against gentamicin-induced renal damage [62]. Matiz G., Osorio M.R., Camacho F., Atencia M., Herazo J. It significantly enhances the trans-epidermal release of -tocopherol (vitamin E), retinyl acetate (vitamin A), pyridoxine (vitamin B6), and ascorbic acid (vitamin C) from topical emulsions in reconstructed human epidermis [101]. It should be noted that there were some side effects, such as burning and redness that disappeared within a few minutes of completing the application [39]. bliss doterra citrus blend ml essential oil invigorating It is also an effective anthelmintic agent against gastrointestinal nematodes; five times more effective on Haemonchus contortus eggs than tea tree EO [51]. In addition, bitter orange EO inhibits the growth of Penicillium digitatum, and P. italicum [15,53]. Russo R., Cassiano M.G.V., Ciociaro A., Adornetto A., Varano G.P., Chiappini C., Berliocchi L., Tassorelli C., Bagetta G., Corasaniti M.T. Prolonged exposure (for 2 weeks) to lemon EO induces significant changes in neuronal circuits involved in anxiety and pain in rats [96]. vitality The fact that several oils In addition, it has been shown to reduce neuronal damage caused in vitro by excitotoxic stimuli by preventing an injury-induced decrease of phosphorylated protein kinase B (phospho-Akt) and phosphorylated glycogen synthase kinase 3 (phospho-GSK-3) levels [137,138]. Williamson E.M., Priestley C.M., Burgess I.F. However, there is a possible skin sensitization issue if old or oxidized oil is used. Stevi T., Beri T., avikin K., Sokovi M., Goevac D., Dimki I., Stankovi S. Antifungal activity of selected essential oils against fungi isolated from medicinal plant. Also, adding an antioxidant to preparations containing Citrus oils is recommended [8]. Bergamottin and 5-geranyloxy-7-methoxycoumarin were identified as the bioactive molecules responsible for the cytotoxic effect of bergamot EO [133]. Improvement of the acne condition was observed with 4375% clearance of lesions. Lemon EO improves creativity and mood, and is thought to affect heart rhythm [97]. Bagetta G., Morrone L.A., Rombol L., Amantea D., Russo R., Berliocchi L., Sakurada S., Sakurada T., Rotiroti D., Corasaniti M.T. No irritation or sensitization data were found for the expressed lime oil. The objective of this review is to summarize the reported biological activities and safety of the essential oils of sweet orange (Citrus sinensis L.), bitter orange (Citrus aurantium L.), neroli (Citrus aurantium L.), orange petitgrain (Citrus aurantium L.), mandarin (Citrus reticulata Blanco), lemon (Citrus limon Osbeck), lime (Citrus aurantifolia), grapefruit (Citrus paradisi Macfady), bergamot (Citrus bergamia Risso & Poit), Yuzu (Citrus junos Sieb. Dugo P., Mondello L., Sebastiani E., Ottan R., Errante G., Dugo G. Identification of minor oxygen heterocyclic compounds of citrus essential oils by liquid chromatography-atmospheric pressure chemical ionisation mass spectrometry. Wattenberg L., Coccia J.B. Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone carcinogenesis in mice by D-limonene and citrus fruit oils.

Jayaprakasha G., Murthy K.C., Demarais R., Patil B. Inhibition of prostate cancer (LNCaP) cell proliferation by volatile components from Nagami kumquats. The key volatile components are presented in Figure 1. Anti-platelet effects of yuzu extract and its component. It is neither toxic nor irritable to skin. It is non-toxic, and is very minimally skin reactive [8]. The use of old or oxidized oils should be avoided. It caused an 89.6% decrease of Eimeria-induced coccidiosis contamination with 5 mg/kg for 30 days [124]. It is used in combination with thyme oil to improve the quality traits of marinated chicken meat [38]. -pinene was irritating at concentrations of 7080%, a weak irritant at 50%, and a non-irritant at concentrations of 2530% to dermatitis patients [195]. Schlede E., Aberer W., Fuchs T., Gerner I., Lessmann H., Maurer T., Rossbacher R., Stropp G., Wagner E., Kayser D. Chemical substances and contact allergy244 substances ranked according to allergenic potency. The antimicrobial effects of.

flowers, peel, young leaves and twigs to whole small immature fruit. Kuwahata H., Komatsu T., Katsuyama S., Corasaniti M.T., Bagetta G., Sakurada S., Sakurada T., Takahama K. Peripherally injected linalool and bergamot essential oil attenuate mechanical allodynia via inhibiting spinal ERK phosphorylation. It also showed a good anti-aflatoxigenic effects (inhibited aflatoxin B1) at 500 ppm [44]. aromatherapy citrus Citrus oils are most plentiful in the oil glands of fruit

Edible Medicinal and Non-Medicinal Plants. Citrus Essential Oils: Flavor and Fragrance. Prevention of glutamate accumulation and upregulation of phospho-Akt may account for neuroprotection afforded by bergamot essential oil against brain injury induced by focal cerebral ischemia in rat. No positive skin reactions were observed when testing the 97% pure linalool at 20%, or to oxidized linalool tested at 1% in dermatitis and eczema patients [175,181]. A pilot study performed in the waiting room of a mental health treatment center (Utah, USA) revealed that inhalation of bergamot EO for 15 minutes improves positive feelings [141]. Similar to diazepam, bergamot oil exerted anxiolytic-like behaviors and attenuated hypothalamic-pituitary-adrenal (HPA) axis activity via reducing the corticosterone response to acute stress caused by EPM [140]. Raw materials range from buds, Fagodia S.K., Singh H.P., Batish D.R., Kohli R.K. Phytotoxicity and cytotoxicity of, Fouad H.A., da Camara C.A.G.

Furthermore, bitter orange EO showed potent fumigant and anti-cholinesterase activities against the silverleaf whitefly, Bemisia tabaci [67]. Fumigant toxicity of. It is worth noting that there is a great variation in the chemical composition of Citrus oils due to differences in origin, genetic background, season, climate, age, ripening stage, method of extraction, etc. It efficiently inhibits adipogenesis via inhibiting the accumulation of triglycerides [117]. Niijima A., Nagai K. Effect of Olfactory stimulation with flavor of grapefruit oil and lemon oil on the activity of sympathetic branch in the white adipose tissue of the epididymis. Evaluation of a three-exposure mouse bone marrow micronucleus protocol: Results with 49 chemicals. It presents an extremely low risk of skin sensitization [8]. It exerted its antianxiety effects by regulating 5-HT receptors in rats [57]. Zhu L.F., Li Y.H., Li B.L., Lu B.Y., Xia N.H. Aromatic Plants and Their Essential Constitutes. The Essential Oils Complete Reference Guide: Over 250 Recipes for Natural Wholesome Aromatherapy. Bergamot EO inhibited tumor formation by the carcinogen NDMA in vitro by more than 70% [136]. It also induced apoptosis in HL-60 cells due to the presence of citral, decanal, and octanal [28]. [15,16,17,18,19]. Sawamura M., Hasegawa K., Kashiwagi T., Nguyen Thi L.-P., Wada M., Kumagai C. Determination of bergapten in Japanese citrus essential oils. It is neither irritating nor sensitizing at 20% [167]. To avoid oxidation of d-limonene, Citrus oils should be stored in a dark air-tight container and placed at 4 C [8]. The antibacterial activity of bitter orange EO was manifested by inhibiting the growth of Listeria innocua, Salmonella enterica, Escherichia coli, Pseudomonas fluorescens, and Aeromonas hydrophila [53,63,64]. A Moysan A., Morlire P., Averbeck D., Dubertret L. Evaluation of phototoxic and photogenotoxic risk associated with the use of photosensitizers in suntan preparations: Application to tanning preparations containing bergamot oil.

Mitropoulou G., Fitsiou E., Spyridopoulou K., Tiptiri-Kourpeti A., Bardouki H., Vamvakias M., Panas P., Chlichlia K., Pappa A., Kourkoutas Y. Viuda-Martos M., Ruiz-Navajas Y., Fernndez-Lpez J., Perez-lvarez J. Antifungal activity of lemon (, Ali N., Chhetri B., Dosoky N., Shari K., Al-Fahad A., Wessjohann L., Setzer W. Antimicrobial, antioxidant, and cytotoxic activities of. Yuzu EO inhibited the formation of the carcinogen N-nitrosodimethylamine (NDMA) in vegetables (by 2259%) and saliva (by 2462%) [149]. The .gov means its official. The expressed bergamot oil was neither irritating nor sensitizing to 25 volunteers when tested at 10% [167]. The acute dermal LD50 of -pinene was >5 g/kg in rabbits, subcutaneous LD50 was 1.42 g/kg in mice, and the acute oral LD50 was >5 g/kg in rats [167]. An experimental study on the effectiveness of massage with aromatic ginger and orange essential oil for moderate-to-severe knee pain among the elderly in Hong Kong. This table is d-Limonene has been shown to possess antioxidant, anti-inflammatory [12], and anticarcinogenic [8] effects. Roberto D., Micucci P., Sebastian T., Graciela F., Anesini C. Antioxidant activity of limonene on normal murine lymphocytes: Relation to H. Kostova I., Bhatia S., Grigorov P., Balkansky S., Parmar V.S., Prasad A.K., Saso L. Coumarins as antioxidants. Sensitivity to 35 essential oils. The analgesic effect of lemon EO is induced by dopamine-related activation of anterior cingulate cortex (ACC) and the descending pain inhibitory system [98]. Neroli EO is used as a sedative for its soothing, calming, and motor relaxant effects by healthcare centers in Puerto Rico, Guatemala, Mexico, Italy, Martinique, and Spain [55]. Young A.R., Walker S.L., Kinley J.S., Plastow S.R., Averbeck D., Morlire P., Dubertret L. Phototumorigenesis studies of 5-methoxypsoralen in bergamot oil: Evaluation and modification of risk of human use in an albino mouse skin model. Yavari Kia P., Safajou F., Shahnazi M., Nazemiyeh H. The effect of lemon inhalation aromatherapy on nausea and vomiting of pregnancy: A double-blinded, randomized, controlled clinical trial. The effects of olfactory stimuli on scholastic performance. Citrus waste is a valuable source of d-limonene, flavonoids, carotenoids, dietary fibers, soluble sugars, cellulose, hemicellulose, pectin, polyphenols, ascorbic acid, methane, and essential oils [4,5,6]. The oil is used to facilitate wound healing [132]. Rudzki E., Grzywa Z., Bruo W.S. Komiya M., Takeuchi T., Harada E. Lemon oil vapor causes an anti-stress effect via modulating the 5-HT and DA activities in mice.

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